D-ALLOSE: A RARE SUGAR TO SWEETEN CANCER CELLS

Abstract

D-Allose is considered a rare sugar with potential to regulate glucose metabolism. In this review of the literature, scientific evidence is presented to support the role of D-Allose as an antiproliferative inhibitor of a variety of cancers by principally up-regulating the Thioredoxin-Interacting Protein. Due to the multiple chemical and enzymatic ways to produce D-Allose and its safety; this low-calorie sugar could be proposed as an ingredient for functional foods for cancer under chemotherapy treatment.